ISO INTERNATIONAL STANDARD 16702 Second edition 2007-12-15 Workplace air quality Determination of total organic isocyanate groups in air using 1-(2-methoxyphenyl)piperazine and liquid chromatography Qualite de I'air des lieux de travail Dosage des groupements isocyanates organiques totaux dans I'air par dérivatisation avec la 1-(2-methoxyphényl)pipérazine et par chromatographie en phase liquide Reference number ISO 16702:2007(E) @ ISO 2007 IHS under ted without license from IHS Not for Resale ISO 16702:2007(E) PDF disclaimer This PDF file may contain embedded typefaces. In accordance with Adobe's licensing policy, this file may be printed or viewed but shall not be edited unless the typefaces which are embedded are licensed to and installed on the computer performing the editing. In accepts no liability in this area. Adobe is a trademark of Adobe Systems Incorporated. Details of the software products used to create this PDF file can be found in the General Info relative to the file; the PDF-creation parameters were optimized for printing. Every care has been taken to ensure that the file is suitable for use by IsO member bodies. In the unlikely event that a problem relating to it is found, please inform the Central Secretariat at the address given below COPYRIGHTPROTECTEDDOCUMENT @ISO2007 All rights reserved. Unless otherwise specified, no part of this publication may be reproduced or utilized in any form or by any means, IsO's member body in the country of the requester. ISO copyright office Case postale 56 . CH-1211 Geneva 20 Tel.+ 4122 749 0111 Fax + 41 22 749 09 47 E-mail [email protected] Web www.iso.org Published in Switzerland @ ISo 2007 - All rights reserved ed without license from IHS Not for Resale ISO 16702:2007(E) Contents Page Foreword. Introduction vi 1 Scope 2 Normative references . 3 Terms and definitions.. 4 Principle.... 5 Reagents and materials 6 Apparatus.. 7 Sampling .... 7.1 Calibration of pump .... 7.2 7.3 Preparation of sampling equipment (general) ... 7.4 Preparation of sampling equipment (filters)... 7.5 Preparation of sampling equipment (impingers). 7.6 Coliection of filter samples (vapour phase samples) 8 7.7 Collection of impinger backed by filter samples (isocyanate aerosols)..... 7.8 Measurements to be made at the end of the sampling period..... 7.9 Sample logging and field desorption of samples.. 7.10 Transportation.......... 7.11 Field Blanks 10 8 Procedure. 10 8.1 Safety precautions. 10 8.2 Cleaning of glassware.. 10 8.3 Prereaction of impinger samples before HPLC analysis...... 8.4 Prereaction of filter samples before HPLC analysis .... 10 8.5 HPLC conditions .... 10 8.6 Determination of airborne isocyanate for monomeric isocyanates (UV detection) .... 11 8.7 Identification of polymeric isocyanates: Ec/UV ratio approach .... 11 8.8 Confirmation of identification for polymeric isocyanates (prepolymers)... 12 8.9 Quantification of airborne isocyanate for polymeric isocyanates (Ec detection)... 13 8.10 Sampling efficiency .... 13 9 Calculations. 14 10 Interferences 14 11 Uncertainty of measurement 14 11.1 introduction... .14 11.2 Assessment of performance characteristics of the method - Sampling considerations .16 11.3 Assessment of performance characteristics of the method - Otherconsiderations (detailed ISO/IEC Guide 98:1995 approach).. 17 11.4 Mass of compound in field sample blank... 21 11.5 Between-laboratory uncertainty contributions. .22 11.6 Combined uncertainty .... 22 11.7 Expanded uncertainty 22 12 Stability . 22 13 Test report 22 Copyrght International Organization forstandardizalon ghts reserved ili Not for Resale ISO 16702:2007(E) 14 Quality control.. Annex A (informative) Determination of sampling efficiency ... Annex B (informative) Data used for uncertainty estimates ..... Annex C (informative) Combined uncertainties for isocyanate formulations Annex D (informative) Sample chromatograms @ ISO 2007 - All rights reserved vided by IHS under lic ed without license from IHS Not for