论文标题
深度学习光子计数CT中的材料分解
Deep Learning for Material Decomposition in Photon-Counting CT
论文作者
论文摘要
光子计数CT(PCCT)通过更好的空间和能量分辨率提供了改进的诊断性能,但是开发可以处理这些大型数据集的高质量图像重建方法是具有挑战性的。 基于模型的解决方案结合了物理习得的模型,以重建更准确的图像,但取决于准确的远期操作员,并在寻找良好的正则化方面遇到了困难。另一种方法是深度学习的重建,这在CT中表现出了巨大的希望。但是,完全数据驱动的解决方案通常需要大量的培训数据,并且缺乏解释性。为了结合两种方法的好处,同时最大程度地降低了各自的缺点,希望开发结合基于模型和数据驱动方法的重建算法。在这项工作中,我们基于展开/展开的迭代网络提出了一种新颖的深度学习解决方案,用于PCCT中的材料分解。我们评估了两种情况:一种学识渊博的后处理,它隐式地利用了模型知识,以及一种学到的梯度淡淡,该梯度在体系结构中具有明确的基于模型的组件。借助我们提出的技术,我们解决了一个具有挑战性的PCCT模拟情况:低剂量,碘对比度和较小的训练样品支持的腹部成像中的三材料分解。在这种情况下,我们的方法的表现优于最大似然估计,一种变异方法以及一个完整的网络。
Photon-counting CT (PCCT) offers improved diagnostic performance through better spatial and energy resolution, but developing high-quality image reconstruction methods that can deal with these large datasets is challenging. Model-based solutions incorporate models of the physical acquisition in order to reconstruct more accurate images, but are dependent on an accurate forward operator and present difficulties with finding good regularization. Another approach is deep-learning reconstruction, which has shown great promise in CT. However, fully data-driven solutions typically need large amounts of training data and lack interpretability. To combine the benefits of both methods, while minimizing their respective drawbacks, it is desirable to develop reconstruction algorithms that combine both model-based and data-driven approaches. In this work, we present a novel deep-learning solution for material decomposition in PCCT, based on an unrolled/unfolded iterative network. We evaluate two cases: a learned post-processing, which implicitly utilizes model knowledge, and a learned gradient-descent, which has explicit model-based components in the architecture. With our proposed techniques, we solve a challenging PCCT simulation case: three-material decomposition in abdomen imaging with low dose, iodine contrast, and a very small training sample support. In this scenario, our approach outperforms a maximum likelihood estimation, a variational method, as well as a fully-learned network.