论文标题
用于定义硼中子捕获疗法中子梁的新数据
New data for the definition of neutron beams for Boron Neutron Capture Therapy
论文作者
论文摘要
硼中子捕获疗法(BNCT)是一种中子放疗,用于治疗先前用硼-10掺杂的肿瘤细胞。这种疗法需要一个以使者中子束来治疗深肿瘤和浅肿瘤的热束。多亏了最近的高电流商业加速器,基于加速器的中子来源(ABN)是提供医院治疗性中子束的竞争选择。在这项工作中,$^7 $ li(p,n)$^7 $以$ 1950〜 $ keV的反应为ABN中的中子源产生的中子字段,这是ABN中的中子源,这是由西班牙裔工厂(西班牙)的飞行时间(TOF)技术衡量的。此外,通过Monte Carlo Simulates(MCNP)评估了BNCT的两个专门为$ 1950〜 $ KEV中子场设计的深层和浅肿瘤治疗的光束塑形组件(BSA)。结果与国际原子能局(IAEA)的绩效数字一致。
Boron Neutron Capture Therapy (BNCT) is a neutron radiotherapy used to treat tumours cells previously doping with Boron-10. This therapy requires an epithermal neutron beam for the treatment of deep tumours and a thermal beam for shallow ones. Thanks to recent high-current commercial accelerators, Accelerator-Based Neutron Sources (ABNS) are competitive option for providing therapeutic neutron beams in hospitals. In this work, the neutron field generated by the $^7$Li(p,n)$^7$Be reaction at $1950~$keV is studied as neutron source in ABNS, being measured by the Time-Of-Flight (TOF) technique at HiSPANoS facility (Spain). Moreover, two Beam Shaping Assemblies (BSA) for deep and shallow tumour treatment, which are specially designed for the $1950~$keV neutron field, are evaluated for BNCT via Monte Carlo simulations (MCNP). Results in agreement with the International Atomic Energy Agency (IAEA) figures of merit endorse the use of this neutron field for BNCT.