论文标题
在墨西哥,芬兰和冰岛建模COVID-19
Modelling Covid-19 epidemic in Mexico, Finland and Iceland
论文作者
论文摘要
在过去的二十年中,有许多全球病毒疾病爆发。这加快了为疾病扩散建模和预测疾病的努力,以找到局限区域和区域之间扩散的方法。在此方面,我们设计了一种由于人类空间迁移率而导致病毒感染的地理传播模型,并将其改编成最新的Covid-19-19大流行。在此中,要建模的区域用二维网格与人口密度定义的细胞加权,在每个网格中,延迟差方程的隔室SEIRS系统模拟了该疾病的局部动力学(微动力学)。细胞之间的感染是随机的,允许病毒在二维空间(宏观动力学)上的地理扩散。这种方法允许将与疾病的生物学方面相关的参数与代表空间传染性行为的参数通过用作病毒载体的人的各种流动性。这些提供了足够的信息来追踪不同情况下大流行的演变。特别是,我们在许多方面将这种方法应用于墨西哥,芬兰和冰岛的三种方式,发现该模型能够再现和预测大流行的随机全球路径。这项研究阐明了一个国家的多样化文化和社会经济方面如何影响流行病的演变以及社会疏远和其他拘留措施的效力。
Over the past two decades there has been a number of global outbreaks of viral diseases. This has accelerated the efforts to model and forecast the disease spreading, in order to find ways to confine the spreading regionally and between regions. Towards this we have devised a model of geographical spreading of viral infections due to human spatial mobility and adapted it to the latest COVID-19 pandemic. In this the region to be modelled is overlaid with a two-dimensional grid weighted with the population density defined cells, in each of which a compartmental SEIRS system of delay difference equations simulate the local dynamics (microdynamics) of the disease. The infections between cells are stochastic and allow for the geographical spreading of the virus over the two-dimensional space (macrodynamics). This approach allows to separate the parameters related to the biological aspects of the disease from the ones that represent the spatial contagious behaviour through different kinds of mobility of people acting as virus carriers. These provide sufficient information to trace the evolution of the pandemic in different situations. In particular we have applied this approach to three in many ways different countries, Mexico, Finland and Iceland and found that the model is capable of reproducing and predicting the stochastic global path of the pandemic. This study sheds light on how the diverse cultural and socioeconomic aspects of a country influence the evolution of the epidemics and also the efficacy of social distancing and other confinement measures.