论文标题
ECG-DELNET:使用神经网络的混合质量标记的心理心电图的描述
ECG-DelNet: Delineation of Ambulatory Electrocardiograms with Mixed Quality Labeling Using Neural Networks
论文作者
论文摘要
心电图(ECG)检测和描述是临床实践中众多任务的关键步骤,因为ECG是评估心脏状况最多的非侵入性测试。最先进的算法采用数字信号处理(DSP),需要适应新形态的规则。相比之下,深度学习(DL)算法,尤其是用于分类的算法,在学术和工业环境中正在增加体重。但是,缺乏模型解释性和小数据库阻碍了其适用性。我们证明,通过将ECG检测和描述嵌入到分段框架上,可以成功地应用于低解释性任务。为此,我们改编并验证了最常用的图像分割的神经网络体系结构,即U-NET,为一维数据。该模型是使用Physionet的QT数据库训练的,该数据库由105个非门诊ECG记录组成,用于单铅场景。为了减轻数据稀缺性,尝试使用数据正则化技术,例如使用低质量数据标签进行预训练,进行基于ECG的数据增强并将强大的模型正规化器应用于体系结构。评估了模型能力(U-NET的深度和宽度)的其他变化,以及最新添加的应用。这些变化以5倍的交叉验证方式进行了详尽的验证。最佳性能配置的精度分别为90.12%,99.14%和98.25%,在与基于DSP的方法的情况下,P,QRS和T波分别为98.73%,99.94%和99.88%。尽管是一种在小型数据集上训练的渴望数据,但基于DL的方法证明是传统基于DSP的ECG处理技术的可行替代方法。
Electrocardiogram (ECG) detection and delineation are key steps for numerous tasks in clinical practice, as ECG is the most performed non-invasive test for assessing cardiac condition. State-of-the-art algorithms employ digital signal processing (DSP), which require laborious rule adaptation to new morphologies. In contrast, deep learning (DL) algorithms, especially for classification, are gaining weight in academic and industrial settings. However, the lack of model explainability and small databases hinder their applicability. We demonstrate DL can be successfully applied to low interpretative tasks by embedding ECG detection and delineation onto a segmentation framework. For this purpose, we adapted and validated the most used neural network architecture for image segmentation, the U-Net, to one-dimensional data. The model was trained using PhysioNet's QT database, comprised of 105 ambulatory ECG recordings, for single- and multi-lead scenarios. To alleviate data scarcity, data regularization techniques such as pre-training with low-quality data labels, performing ECG-based data augmentation and applying strong model regularizers to the architecture were attempted. Other variations in the model's capacity (U-Net's depth and width), alongside the application of state-of-the-art additions, were evaluated. These variations were exhaustively validated in a 5-fold cross-validation manner. The best performing configuration reached precisions of 90.12%, 99.14% and 98.25% and recalls of 98.73%, 99.94% and 99.88% for the P, QRS and T waves, respectively, on par with DSP-based approaches. Despite being a data-hungry technique trained on a small dataset, DL-based approaches demonstrate to be a viable alternative to traditional DSP-based ECG processing techniques.