论文标题
深脑刺激手术中的图像指导治疗帕金森氏病：评论
Image guidance in deep brain stimulation surgery to treat Parkinson's disease: a review
论文作者
论文摘要
深脑刺激（DBS）是一种有效的疗法，可替代帕金森氏病（PD）的药物治疗方法。除了仪器，治疗计划和手术方案之类的因素外，该过程的成功在很大程度上取决于电极在最佳治疗靶标内的准确放置，同时避免了可能导致手术并发症和不良神经系统影响的重要结构。尽管DBS的特定手术技术可能会有所不同，但医学成像的介入指导极大地有助于该过程的开发，结果和安全性。随着新型成像技术，计算方法和手术导航软件的快速发展，以及对DBS疾病和作用机理的洞察力，有望进一步提高该程序治疗PD的能力和功效。本文调查了图像引导的DBS手术中最新的技术来治疗PD，并讨论其优势和缺点，以及关于该主题的未来方向。
Deep brain stimulation (DBS) is an effective therapy as an alternative to pharmaceutical treatments for Parkinson's disease (PD). Aside from factors such as instrumentation, treatment plans, and surgical protocols, the success of the procedure depends heavily on the accurate placement of the electrode within the optimal therapeutic targets while avoiding vital structures that can cause surgical complications and adverse neurologic effects. While specific surgical techniques for DBS can vary, interventional guidance with medical imaging has greatly contributed to the development, outcomes, and safety of the procedure. With rapid development in novel imaging techniques, computational methods, and surgical navigation software, as well as growing insights into the disease and mechanism of action of DBS, modern image guidance is expected to further enhance the capacity and efficacy of the procedure in treating PD. This article surveys the state-of-the-art techniques in image-guided DBS surgery to treat PD, and discuss their benefits and drawbacks, as well as future directions on the topic.
