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Bayesian optimization is a class of data efficient model based algorithms typically focused on global optimization. We consider the more general case where a user is faced with multiple problems that each need to be optimized conditional on a state variable, for example given a range of cities with different patient distributions, we optimize the ambulance locations conditioned on patient distribution. Given partitions of CIFAR-10, we optimize CNN hyperparameters for each partition. Similarity across objectives boosts optimization of each objective in two ways: in modelling by data sharing across objectives, and also in acquisition by quantifying how a single point on one objective can provide benefit to all objectives. For this we propose a framework for conditional optimization: ConBO. This can be built on top of a range of acquisition functions and we propose a new Hybrid Knowledge Gradient acquisition function. The resulting method is intuitive and theoretically grounded, performs either similar to or significantly better than recently published works on a range of problems, and is easily parallelized to collect a batch of points.